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Cialis: How it Works

  • Cialis is a worldwide recognized pharmaceutical product where Tadalafil is the active substance.
  • The active substance in medication impedes the action of enzyme called PDE5. The enzyme demolishes cGMP which makes the relaxation of smooth muscles possible. When the action of PDE5 is impeded, this leads to the stimulation of cGMP production in the body. Consequently, high cGMP concentrations contribute to dilating of blood vessels.
  • Penis, lungs, and retina contain the highest PDE5 concentrations. But the other blood vessels and smooth muscles also contain this enzyme.
  • Tadalafil is in the list of the best PDE5 suppressors.

Advantages

  • Cialis is the medication for curing erectile dysfunction. The medication intensifies blood circulation in the penis in the response to sexual arousal. It helps men attain and sustain a full erection.
  • The medication is also intended for relieving symptoms and curing benign prostatic hyperplasia.
  • The medication may be used every day. It’s not necessary to plan sexual intercourse when undergoing Tadalafil treatment.
  • The duration of drug action is approximately 36 hours.

Disadvantages

Men from 18 to 60 years old can use Cialis. The men shouldn’t have any diseases. They also shouldn’t undergo pharmacological therapy. If you conform to these requirements, these adverse effects may still occur:

  • Blush, headache, digestive disturbance, notalgia, and nasal blockage belong to the most frequently experienced adverse effects.
  • Hypotension, melalgia, muscle ache, and conjunctivitis are in the list of less widespread adverse effects.
  • Sudden loss of vision which is the result of impaired blood supply to the optic nerve is one of the rare adverse effects.
  • Acoustic disturbance and priapism belong to the rare adverse effects. If the erection duration exceeds 4-6 hours, you must visit the healthcare practitioner.
  • Stethalgia, angina, cardiovascular diseases, severe kidney disorders, severe liver disorders, Peyronie’s disease, eye disorders, haemorrhagic disease, and gastric ulceration are the reasons for which the medication is contraindicative for men.
  • The medication can’t be combined with nitrate drugs, as well as with the medications containing ritonavir and ketoconazole.
  • Low dose of medication may be suitable for men with mild-to-moderate kidney disease and liver disease.

In brief, old men, men with cardiovascular diseases, convulsionary attacks, diabetes, kidney disorders, and liver disorders, as well as men who use some medications may face different adverse effects.

Bottom Line

Cialis is a drug effective for curing erectile dysfunction and decreasing symptoms of benign prostatic hyperplasia. The duration of drug action is up to 36 hours. It’s possible to take low dose of ED medication every day to avoid planning of sexual intercourse.

Recommendations

  • Medication intake time shouldn’t be changed if you use Cialis every day.
  • Avoid alcohol once you have taken the medicine since alcohol may cause hypotension and worsen sexual activity.
  • You shouldn’t combine the medication with grapefruit or grapefruit juice consumption.
  • Visit your doctor before starting any ED treatment.
  • If you face any adverse effects after the medication intake, get in touch with the healthcare practitioner without delay.
  • Cialis is incompatible with nitrate medications, supplements with natural Viagra effect and party drugs.
  • Trust only well-reputed suppliers when purchasing the medication.
  • Cialis ensures no protection against sexually transmitted diseases.
  • Allergic reaction, priapism, and sudden loss of vision demand urgent medical care.

Medication Efficacy

The maximum plasma concentrations of active substance are measured between 30 minutes and 6 hours after the intake. The initial dose of Cialis has to be 2.5 mg per day to fix ED; 5 mg per day to treat BPH; and 10 mg to get ready for sexual intercourse. Individual dosage adjustments are possible.
 

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